Immunology

Cytokines and the CNS by Richard M. Ransohoff, Etty N. Benveniste

By Richard M. Ransohoff, Etty N. Benveniste

Provides perception into How Cytokine motion affects the body structure and Pathology of the CNS.

As with the 1st variation of Cytokines and the CNS, this thoroughly up to date and revised version introduces neurobiologists to cytokine biology and immunologists to the original services of cytokines in CNS body structure. The dramatically accelerating curiosity in cytokines and cytokine/chemokine signaling during the last numerous years has inspired an explosion of literature on cytokines. The similarity among elements keen on irritation or immunity, and people implicated in neural improvement, body structure, and service has develop into so obvious that familiarity with cytokines needs to now be thought of a vital aspect within the neurobiologist’s cognitive tool-kit. Conversely, for immunobiologists, the ideas elaborated through neurobiologists to appreciate developmental patterning and networked organ functionality proceed to adapt in this type of means that comprehension of cytokine motion within the CNS can simply increase one other realizing of immune method function. 

Cytokines and the CNS, Second Edition is patterned after the 1st version; although, the wealth of information now on hand provides an enormous quantity of perception and new implications. to assure a clean viewpoint, the editors made a unsleeping option to make the most of a completely new set of individuals, all specialists in quite a few facets of cytokine learn.

Cytokines and the CNS, Second Edition starts off with a bankruptcy at the CNS, concentrating on pathological reactions to insult. subsequent, come 3 chapters on cytokine biology, by way of 4 chapters that combine cytokine biology into easy CNS strategies (development; irritation; immunity; degeneration/repair), and then 5 chapters observe this physique of data to ailment or pathology. The publication closes with a glance on the program of cytokine biology to the therapy of ailment, a new quarter of research.В 

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Natl. Acad. Sci. U. S. A. 101, 3533, 2004. 105. Hemmi H. et al. The roles of two Ikappab kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection, J. Exp. Med. 199, 1641, 2004. 106. K. et al. Differential requirement for TANK-binding Kinase-1 in Type I interferon responses to Toll-like receptor activation and viral infection, J. Exp. Med. 199, 1651, 2004. 107. H. et al. Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions, Am.

Historical review: cytokines as therapeutics and targets of therapeutics, Trends Pharmacol Sci 25 (4), 201–9, 2004. 8. , Bigazzi, P. , Commentary. Similarities of T cell function in cell-mediated immunity and antibody production, Cellular Immunology 12 (1), 150–9, 1974. 9. Oppenheim, J. J. , Introduction to the role of cytokines in innate host defense and adaptive immunity, In Cytokine Reference 1, Oppenheim, J. J. , Academic Press, 2001, pp. 3–20. 10. , Thomson, A. W. and Lotze, M. , Academic Press, 2003, pp.

Cytokines, chemokines, and cytokine receptors in human microglia, J. Neurosci. Res. 69, 94, 2002. 52. Meda L. et al. Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid [25–35], J. Neuroimmunol. 93, 45, 1999. 53. C. et al. Cytokine production by human fetal microglia and astrocytes: differential induction by LPS and IL-1β, J. Immunol. 150, 2659, 1993. 54. H. et al. , J. Immunol. 161, 1989, 1998. 55. , and Lee S. C. Glial cytokine expression in human CNS culture following hypoxia, Soc.

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