Ophthalmology

Current Concepts in Uveal Melanoma (Developments in by M.J. Jager, L. Desjardins, T. Kivelä, B.E. Damato, F.

By M.J. Jager, L. Desjardins, T. Kivelä, B.E. Damato, F. Bandello

Uveal cancer is an competitive kind of melanoma which can contain the iris, the ciliary physique, and/or the choroid, that is the most situation of this tumor. sufferers frequently desire to learn approximately remedy offerings and the result of various methods. very important present medical questions are no matter if a biopsy can be taken of choroidal melanomas, what may be performed with this biopsy, and no matter if high-risk sufferers can be screened frequently. This quantity describes the medical features of uveal cancer in addition to the several present suggestions on hand for therapy, akin to radioactive plaque remedy, proton beam treatment, and native tumor resection. moreover, strategies for taking biopsies and characterizing biopsy fabric are confirmed. destiny remedies similar to anti-VEGF therapy and techniques for the therapy of metastases also are mentioned. citizens with an curiosity in ocular oncology, ophthalmologists or physicians facing uveal cancer, in addition to sufferers wishing to grasp extra approximately this malignancy will discover a topical replace on uveal cancer during this e-book.

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Current Concepts in Uveal Melanoma (Developments in Ophthalmology)

Uveal cancer is an competitive kind of melanoma which may contain the iris, the ciliary physique, and/or the choroid, that is the most position of this tumor. sufferers frequently desire to be told approximately remedy offerings and the result of diverse ways. vital present scientific questions are no matter if a biopsy will be taken of choroidal melanomas, what could be performed with this biopsy, and even if high-risk sufferers could be screened frequently.

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Extra resources for Current Concepts in Uveal Melanoma (Developments in Ophthalmology)

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Irradiation to the anterior segment often causes anterior uveitis, which should be treated in advance by high doses of corticosteroids and cycloplegics, in order to prevent its complications. Combined Use of Ru-106 Brachytherapy with Other Treatment Modalities Ru-106 applicators are usually used alone for the treatment of uveal melanoma, but in some centers they have been used in combination with other known modalities of treatment for uveal melanoma. 36 Pe’er Combined Ru-106 brachytherapy and transpupillary thermotherapy for treating uveal melanoma is sometimes used, and is termed ‘sandwich therapy’ [60].

Br J Ophthalmol 2009;93:1167–1171. Pe’er 33 Tanandeh H, Chaudhry NA, Murray TG, Ehlies F, Hughes R, Scott IU, Markoe AM: Intraoperative echographic localization of iodine-125 episcleral plaque for brachytherapy of choroidal melanomas. Am J Ophthalmol 2000;125:199–204. 34 Anteby I, Pe’er J: Need for confirmation of positioning of ruthenium plaques by postoperative B-scan ultrasonography. Ophthalmic Surg Lasers 1996;27: 1024–1029. 35 Damat B, Patel I, Campbell IR, Mayles HM, Errington RD: Visual acuity after ruthenium-106 brachytherapy of choroidal melanoma.

There is scope for comparing different methods of treatment selection and assessing these in terms of patient satisfaction with this process. From what I have heard from my patients, I have gained the impression that there is a tendency for practitioners to mention only the therapeutic modalities that are available in their clinic or hospital, without discussing forms of treatment that are available only at distant locations. For example, I recently saw a patient who had been offered plaque radiotherapy at another centre but who asked to be referred to Liverpool only because she wanted treatment without delay (there being staff sickness at the other centre).

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