Veterinary Medicine

Bovine Genomics by James Womack

By James Womack

The genetic details being unlocked via advances in genomic and excessive throughput applied sciences is quickly revolutionizing our realizing of developmental strategies in bovine species. this data is permitting researchers extraordinary perception into the genetic foundation of key qualities. Bovine Genomics is the 1st booklet to collect and synthesize the knowledge realized throughout the bovine genome sequencing venture and think about its functional program to livestock and dairy construction.

Bovine Genomics opens with foundational chapters at the domestication of farm animals and standard Mendelian genetics. development on those chapters, insurance quickly strikes to quantitative genetics and the advances of complete genome applied sciences. major insurance is given to such issues as epigenetics, mapping quantitative path loci, genome-wide organization reports and genomic choice in livestock breeding. The ebook is a worthy synthesis of the sector written through a world crew of top researchers.

Providing wide-ranging assurance of the subject, Bovine Genomic, is a vital advisor to the sector. the fundamental and utilized technology should be of use to researchers, breeders, and complicated students.

Chapter 1 The Origins of livestock (pages 1–10): Matthew D. Teasdale and Daniel G. Bradley
Chapter 2 Mendelian Inheritance in farm animals (pages 11–19): Frank W. Nicholas
Chapter three Genetics of Coat colour in livestock (pages 20–33): Sheila M. Schmutz
Chapter four From Quantitative Genetics to Quantitative Genomics: a private Odyssey (pages 34–50): Morris Soller
Chapter five Cartography of the Bovine Genome (pages 51–62): James E. Womack
Chapter 6 heritage of Linkage Mapping the Bovine Genome (pages 63–74): Stephanie D. McKay and Robert D. Schnabel
Chapter 7 Bovine X and Y Chromosomes (pages 75–100): F. Abel Ponce de Leon and Wansheng Liu
Chapter eight farm animals Comparative Genomics and Chromosomal Evolution (pages 101–108): Denis M. Larkin
Chapter nine Sequencing the Bovine Genome (pages 109–122): Kim C. Worley and Richard A. Gibbs
Chapter 10 Bovine Genome structure (pages 123–143): David L. Adelson
Chapter eleven Bovine Epigenetics and Epigenomics (pages 144–168): Xiuchun (cindy) Tian
Chapter 12 Mapping Quantitative Trait Loci (pages 169–191): Joel I. Weller
Chapter thirteen Genome?Wide organization experiences and Linkage Disequilibrium in farm animals (pages 192–210): M. E. Goddard and B. J. Hayes
Chapter 14 Genomic choice in red meat livestock (pages 211–233): Jeremy F. Taylor, Stephanie D. McKay, Megan M. Rolf, Holly R. Ramey, Jared E. Decker and Robert D. Schnabel
Chapter 15 effect of High?Throughput Genotyping and Sequencing at the id of Genes and editions Underlying Phenotypic version in family farm animals (pages 234–258): Michel Georges

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It is apparently considered lucky to have one in a dairy herd. Leeb (2008) presented data that this pattern was linked to KIT. 2C). 2D) rather than solid colored (Olson 1999). Interestingly, no researcher has published a mutation in the KIT gene or promoter region that could be a causative mutation for any white marking pattern in cattle yet, even though several years have passed. Is this because some white marking patterns are essentially fixed in a breed? Would there ever be a Hereford without the characteristic white markings?

1987). In 1985, Jim approached us on submitting a BARD proposal for mapping the bovine genome using markers and somatic cell hybrids. This was funded in 1985 and renewed in 1989. On our side, we used the funds primarily for marker development, while Jim went on to develop the comparative bovine/human/mouse synteny map (Dietz et al.

C. (1999) A missense mutation in the bovine MGF gene is associated with the roan phenotype in Belgian Blue and Shorthorn cattle. Mammalian Genome 10: 710–712. , Boettcher, P. (2010) Identification of selection signatures in cattle breeds selected for dairy production. Genetics 185: 1451–1461. U. J. (1970) Spontanes Auftreten von Albinos in der Schweizerischen Braunviehrasse. Schweizer Archiv fur Tierheilkunde 112: 581–587. P1: SFK/UKS BLBS104-04 P2: SFK Womack February 20, 2012 21:49 Trim: 244mm×172mm Chapter 4 From Quantitative Genetics to Quantitative Genomics: A Personal Odyssey Morris Soller Quantitative Genetics: A science of heredity of quantitative traits based on inferences from observed phenotypes.

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