Ophthalmology

Age-Related Macular Degeneration by Jennifer I. Lim

By Jennifer I. Lim

This reference showcases exudative and nonexudative AMD therapy recommendations utilizing argon and diode lasers, submacular and macular translocation surgical procedure, photodynamic remedy, radiation, feeder vessel therapy, thermotherapy, and antiangiogenesis medicinal drugs. together with a hundred and sixty colour illustrations, Age-Related Macular Degeneration will profit medical ophthalmologists, pathologists, physiologists, and pharmacologists; optometrists; mobilephone and molecular biologists and biochemists; retinal experts; AMD researchers; and graduate and clinical institution scholars in those disciplines.

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Extra resources for Age-Related Macular Degeneration

Sample text

11. Willerson DJ, Aaberg TM. Senile macular degeneration and geographic atrophy of the retinal pigment epithelium. Br J Ophthalmol 1978;62:551–553. 12. Dastgheib K, Green WR. Granulomatous reaction to Bruch’s membrane in age-related macular degeneration. Arch Ophthalmol 1994;112:813–818. 13. Penfold PL, Killingsworth MC, Sarks SH. Senile macular degeneration. The involvement of giant cells in atrophy of the retinal pigment epithelium. Invest Ophthalmol Vis Sci 1986;27:364–371. 14. , Woolfson J, Lambert HM.

In many nonlymphoid and lymphoid organs, dendritic cells become a system of antigen-presenting cells. These sites recruit DC by defined migration pathways, and in each site, DC share features of structure and function. DC cells function as accessory cells that play an important role in processing and presentation of antigens to T cells, and their distinctive role is to initiate responses in naive lymphocytes. Thus, DC serve as the most potent leukocytes for activating T-cell-dependent immune responses.

Activation of Antigen-Specfic Immunity. This is often expressed as the concept of the “immune response arc,” which proposes that interaction between antigen and the antigen-specific immune system at a peripheral site (such as the skin) can conceptually be subdivided into three phases: afferent (at the site), processing (within the immune system), and effector (at the original site completing the arc) (1–3,7) (Fig. ) Antigen within the skin or any other site is recognized by the afferent phase of the immune response, which conveys the antigenic information to the lymph node in one of two forms.

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