By Herbert E. Spiegel (ed.)
The sector of medical chemistry now encompasses features of analytical chemistry, biochemistry, medical laboratory technology, toxicology, immunology and molecular biology. This serial presents a extra entire international view of the present and destiny instructions of this increasing self-discipline. This quantity offers topical papers realted frequently to the kidney, melanoma and purposes of the polymerase chain response.
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Increase in the glucosylated form of erythrocyte Cu-Zn-superoxide dismutase in diabetes and close association of the nonenzymatic glucosylation with the enzyme activity. Biochim. Biophys. Acra 924, 292-296 (1987). A7. , Glycation and inactivation of human Cu-Zn-superoxide dismutas: Identification of the in vivo glycated sites. J. Biol. Chem. 262, 16969-16972 (1987). A8. , and Burr, I. , Joint purification of mangano and cuprozinc superoxide dismutases from a single source-A simplified method.
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0.. M. 800- 7I i + I -I a 1 f 400- 2 f y z I- 200- z v) a 0.. 0, M. 17. Typical patterns of Mn-SOD release into serum for two male patients with acute myocardial infarction. (A) A case with an unsuccessful reperfusion; (B) successful case. The mean level for normal male adults is almost 100 ng/ml. Other enzymes: AST, ~-aspartate:2-oxoglutarate;ALT, ~-alanine:2-oxoglutarate; CK, creatine kinase; LDH, lactate dehydrogenase. 01 0 50 100 150 Time from the onset (hours) n 0 y 200. 18. Serial determinations of serum Mn-SODin 29 patients with acute myocardial infarction: (A) 23 cases with successful and (B) 6 cases with unsuccessful reperfusion.