2008-2009 Basic and Clinical Science Course: Section 11: by James C. Bobrow, MD

By James C. Bobrow, MD

This part underwent significant revision for the 2008-2009 version. part eleven experiences the anatomy, body structure, embryology, and pathology of the lens. It additionally covers the epidemiology of cataracts and their evaluate and administration in adults. moreover, an outline of lens and cataract surgical procedure is equipped, issues of cataract surgical procedure are mentioned, and cataract surgical procedure in detailed events is explored. comprises many new photos.

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Additional resources for 2008-2009 Basic and Clinical Science Course: Section 11: Lens and Cataract (Basic and Clinical Science Course 2008-2009)

Example text

In: Isenberg SJ, ed. The Eye ill II/filllcy. 2nd ed. St Louis: Mosby; 1994:336-373. Jaffe NS, Horwitz I. Lens alterations. In: Podos SM, Yanoff M, eds. Textbook of Ophthalmology. Vol 3. 16. Lambert S. Lens. In: Taylor D, cd. Paediatric Ophthalmology. ence; 1997:445-476. Shortt AI, Lanigan B, O'Keefe M. Pars plana lensectomy 2nd ed. Boston: Blackwell Sci- for the management of ectopia lentis in children. J Pediatr Ophthalmol Strabismlls. 2004;41 (5):289-294. Streeten BW. Pathology of the lens. In: Albert DM, Jakobiec FA, eds.

Pentose-P04 TP Phosphofructokinase ADP Fructose-1-6-di-P04 Lactate Lactic 01( dehydrogenase 1 Pyruvate . Krebs citric acid cycle (Tricarboxylic acid cycle) ~ NAD Figure 2-2 NADH Simplified scheme of glucose metabolism in the lens. (AdaptedwithpermissionfromHart WM Jr, ed. Adler's Physiology of the Eye: Clinical Application. 9th ed. 1 additional 36 molecules of ATP from each glucose molecule metabolized in the citric acid cycle (oxidative metabolism). Because of the low oxygen tension in the lens, only about 3% of the lens glucose passes through the Krebs citric acid cycle to produce ATP; however, even this low level of aerobic metabolism produces approximately 25% of the lens ATP.

Sporadic posterior polar cataracts are often unilateral and may be associated with remnants of the tunica vasculosa lent is or with an abnormality of the posterior capsule such as lenticonus or lentiglobus. Sutural The sutural, or stellate, cataract is an opacification of the V-sutures of the fetal nucleus. It usually does not impair vision (Fig 4- I I). These opacities often have branches or knobs projecting from them. Bilateral and symmetric, sutural cataracts are frequently inherited in an autosomal dominant pattern.

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